Overview
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
5.7
USERS' SCORE
Good
Based on 6 Reviews
8.3
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin K2 (as Menaquinone-4) (MK-4)
100 mcg
**
Alfalfa Powder (Aerial Parts)
250 mg
**
Top Medical Research Studies
9
We explored whether vitamin K2, a form of vitamin K, could help in managing high cholesterol and atherosclerosis in rabbits with elevated cholesterol levels.
Over a span of ten weeks, we administered different doses of vitamin K2 to rabbits fed a cholesterol-rich diet.
The findings were encouraging; the vitamin K2-treated rabbits had significantly lower cholesterol levels compared to a control group.
Additionally, it seems that vitamin K2 at moderate doses helped slow down the development of atherosclerosis without any adverse effects on blood coagulation.
Over a span of ten weeks, we administered different doses of vitamin K2 to rabbits fed a cholesterol-rich diet.
The findings were encouraging; the vitamin K2-treated rabbits had significantly lower cholesterol levels compared to a control group.
Additionally, it seems that vitamin K2 at moderate doses helped slow down the development of atherosclerosis without any adverse effects on blood coagulation.
Read More
1
Nutraceuticals ineffective for cholesterol
We conducted a double-blind, placebo-controlled trial to see if a nutraceutical combination including vitamin K could improve cholesterol and inflammation in 118 individuals with high cholesterol.
After 6 and 12 weeks, we found that this combination didn't significantly lower total cholesterol, LDL cholesterol, or triglycerides. It also had no impact on various inflammatory biomarkers.
Our findings indicate that, at the doses used, the nutraceutical combination did not effectively change cholesterol or inflammatory markers.
After 6 and 12 weeks, we found that this combination didn't significantly lower total cholesterol, LDL cholesterol, or triglycerides. It also had no impact on various inflammatory biomarkers.
Our findings indicate that, at the doses used, the nutraceutical combination did not effectively change cholesterol or inflammatory markers.
Read More
7
Vitamin K impacts cholesterol relationship
We examined whether a dietary supplement containing Octacosanol and vitamin K2 could help regulate cholesterol levels for those taking atorvastatin. In a double-blind, placebo-controlled trial with 87 participants over 13 weeks, we didn't see any major changes in overall cholesterol or PCSK9 levels.
However, we found that the relationship between the changes in PCSK9 and LDL cholesterol normalized in participants taking the supplement. This suggests that while cholesterol levels remained steady, the supplement might help improve how these two important factors relate to each other in the context of statin therapy.
However, we found that the relationship between the changes in PCSK9 and LDL cholesterol normalized in participants taking the supplement. This suggests that while cholesterol levels remained steady, the supplement might help improve how these two important factors relate to each other in the context of statin therapy.
Read More
Most Useful Reviews
9
Effective for cholesterol
1 people found this helpful
It is beneficial for those with high cholesterol or harmful fats. I find it essential and encourage others to order it regularly due to its numerous benefits.
Read More
9
Take with K2
If taking high doses of D3 (over 5000), it’s vital to combine it with vitamin K2.
Read More
9
Prevent calcification
I take it for better assimilation of vitamin D3, as high doses might lead to calcification in vessels without vitamin K2.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
5.7
- All Researches
9
We explored whether vitamin K2, a form of vitamin K, could help in managing high cholesterol and atherosclerosis in rabbits with elevated cholesterol levels.
Over a span of ten weeks, we administered different doses of vitamin K2 to rabbits fed a cholesterol-rich diet.
The findings were encouraging; the vitamin K2-treated rabbits had significantly lower cholesterol levels compared to a control group.
Additionally, it seems that vitamin K2 at moderate doses helped slow down the development of atherosclerosis without any adverse effects on blood coagulation.
Over a span of ten weeks, we administered different doses of vitamin K2 to rabbits fed a cholesterol-rich diet.
The findings were encouraging; the vitamin K2-treated rabbits had significantly lower cholesterol levels compared to a control group.
Additionally, it seems that vitamin K2 at moderate doses helped slow down the development of atherosclerosis without any adverse effects on blood coagulation.
Read More
7
Vitamin K impacts cholesterol relationship
We examined whether a dietary supplement containing Octacosanol and vitamin K2 could help regulate cholesterol levels for those taking atorvastatin. In a double-blind, placebo-controlled trial with 87 participants over 13 weeks, we didn't see any major changes in overall cholesterol or PCSK9 levels.
However, we found that the relationship between the changes in PCSK9 and LDL cholesterol normalized in participants taking the supplement. This suggests that while cholesterol levels remained steady, the supplement might help improve how these two important factors relate to each other in the context of statin therapy.
However, we found that the relationship between the changes in PCSK9 and LDL cholesterol normalized in participants taking the supplement. This suggests that while cholesterol levels remained steady, the supplement might help improve how these two important factors relate to each other in the context of statin therapy.
Read More
1
Nutraceuticals ineffective for cholesterol
We conducted a double-blind, placebo-controlled trial to see if a nutraceutical combination including vitamin K could improve cholesterol and inflammation in 118 individuals with high cholesterol.
After 6 and 12 weeks, we found that this combination didn't significantly lower total cholesterol, LDL cholesterol, or triglycerides. It also had no impact on various inflammatory biomarkers.
Our findings indicate that, at the doses used, the nutraceutical combination did not effectively change cholesterol or inflammatory markers.
After 6 and 12 weeks, we found that this combination didn't significantly lower total cholesterol, LDL cholesterol, or triglycerides. It also had no impact on various inflammatory biomarkers.
Our findings indicate that, at the doses used, the nutraceutical combination did not effectively change cholesterol or inflammatory markers.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective for cholesterol
1 people found this helpful
It is beneficial for those with high cholesterol or harmful fats. I find it essential and encourage others to order it regularly due to its numerous benefits.
Read More
9
Take with K2
If taking high doses of D3 (over 5000), it’s vital to combine it with vitamin K2.
Read More
9
Prevent calcification
I take it for better assimilation of vitamin D3, as high doses might lead to calcification in vessels without vitamin K2.
Read More
9
Boosts immunity
Thorne provides superior ingredients and dosage, promoting immunity without taste. It's an economical choice for health.
Read More
7.5
Halal and effective
This halal product is excellent for hair, nails, and skin, while also helping to reduce harmful cholesterol. Suitable for those over 18.
Read More
Frequently Asked Questions
7.5
Halal and effective
This halal product is excellent for hair, nails, and skin, while also helping to reduce harmful cholesterol. Suitable for those over 18.
4
Mixed results
Large size and effective quality, but my mother didn't tolerate it well despite positive reviews. It may still help others with high cholesterol.
9
Effective for cholesterol
1 people found this helpful
It is beneficial for those with high cholesterol or harmful fats. I find it essential and encourage others to order it regularly due to its numerous benefits.
9
Take with K2
If taking high doses of D3 (over 5000), it’s vital to combine it with vitamin K2.
9
Prevent calcification
I take it for better assimilation of vitamin D3, as high doses might lead to calcification in vessels without vitamin K2.
1
Nutraceuticals ineffective for cholesterol
We conducted a double-blind, placebo-controlled trial to see if a nutraceutical combination including vitamin K could improve cholesterol and inflammation in 118 individuals with high cholesterol.
After 6 and 12 weeks, we found that this combination didn't significantly lower total cholesterol, LDL cholesterol, or triglycerides. It also had no impact on various inflammatory biomarkers.
Our findings indicate that, at the doses used, the nutraceutical combination did not effectively change cholesterol or inflammatory markers.
After 6 and 12 weeks, we found that this combination didn't significantly lower total cholesterol, LDL cholesterol, or triglycerides. It also had no impact on various inflammatory biomarkers.
Our findings indicate that, at the doses used, the nutraceutical combination did not effectively change cholesterol or inflammatory markers.
7
Vitamin K impacts cholesterol relationship
We examined whether a dietary supplement containing Octacosanol and vitamin K2 could help regulate cholesterol levels for those taking atorvastatin. In a double-blind, placebo-controlled trial with 87 participants over 13 weeks, we didn't see any major changes in overall cholesterol or PCSK9 levels.
However, we found that the relationship between the changes in PCSK9 and LDL cholesterol normalized in participants taking the supplement. This suggests that while cholesterol levels remained steady, the supplement might help improve how these two important factors relate to each other in the context of statin therapy.
However, we found that the relationship between the changes in PCSK9 and LDL cholesterol normalized in participants taking the supplement. This suggests that while cholesterol levels remained steady, the supplement might help improve how these two important factors relate to each other in the context of statin therapy.
9
We explored whether vitamin K2, a form of vitamin K, could help in managing high cholesterol and atherosclerosis in rabbits with elevated cholesterol levels.
Over a span of ten weeks, we administered different doses of vitamin K2 to rabbits fed a cholesterol-rich diet.
The findings were encouraging; the vitamin K2-treated rabbits had significantly lower cholesterol levels compared to a control group.
Additionally, it seems that vitamin K2 at moderate doses helped slow down the development of atherosclerosis without any adverse effects on blood coagulation.
Over a span of ten weeks, we administered different doses of vitamin K2 to rabbits fed a cholesterol-rich diet.
The findings were encouraging; the vitamin K2-treated rabbits had significantly lower cholesterol levels compared to a control group.
Additionally, it seems that vitamin K2 at moderate doses helped slow down the development of atherosclerosis without any adverse effects on blood coagulation.
References
- Protic O, Di Pillo R, Montesanto A, Galeazzi R, Matacchione G, et al. Randomized, Double-Blind, Placebo-Controlled Trial to Test the Effects of a Nutraceutical Combination Monacolin K-Free on the Lipid and Inflammatory Profile of Subjects with Hypercholesterolemia. Nutrients. 2022;14. doi:10.3390/nu14142812
- Ciric MZ, Ostojic M, Baralic I, Kotur-Stevuljevic J, Djordjevic BI, et al. Supplementation with Octacosanol Affects the Level of PCSK9 and Restore Its Physiologic Relation with LDL-C in Patients on Chronic Statin Therapy. Nutrients. 2021;13. doi:10.3390/nu13030903
- Kawashima H, Nakajima Y, Matubara Y, Nakanowatari J, Fukuta T, et al. Effects of vitamin K2 (menatetrenone) on atherosclerosis and blood coagulation in hypercholesterolemic rabbits. Jpn J Pharmacol. 1997;75:135.
